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Symbol Name ID |
Tgfb1
transforming growth factor, beta 1 MGI:98725 |
| Darker colors indicate more annotations |
| Human Phenotypes | Sinusitis |
Chronic sinusitis |
Pleural effusion |
Recurrent pneumonia |
Asthma |
Recurrent respiratory infections |
Recurrent bronchopulmonary infections |
Recurrent lower respiratory tract infections |
Bronchoconstriction |
Pneumothorax |
Emphysema |
Chronic bronchitis |
Hemoptysis |
Bronchiectasis |
Decreased forced expiratory flow 25-75% |
Reduced forced expiratory volume in one second |
Reduced forced vital capacity |
Airway hyperresponsiveness |
Airway obstruction |
Chronic pulmonary obstruction |
Chronic lung disease |
Hyperpolarized transepithelial nasal potential difference |
| Disease(s) Associated with TGFB1 | ||||||||||||||||||||||
| asthma | ||||||||||||||||||||||
| atopic dermatitis | ||||||||||||||||||||||
| chronic obstructive pulmonary disease | ||||||||||||||||||||||
| cystic fibrosis | ||||||||||||||||||||||
| multiple myeloma | ||||||||||||||||||||||
| pulmonary emphysema |
| Mouse Phenotypes | lung inflammation |
interstitial pneumonia |
abnormal lung morphology |
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| Availability | Mouse Genotype | |||
| Tgfb1tm1Doe/Tgfb1tm1Doe | ||||
| Tgfb1tm1N/Tgfb1tm1N | ||||
| Tgfb1tm1Rif/Tgfb1tm1Rif | ||||
| Tg(Lck-cre)548Jxm/? Tgfb1tm2.1Doe/Tgfb1tm2.1Doe (conditional) |
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| B9d2/Tgfb1tm1Flv/Tgfb1tm2Flv Tg(Cd4-cre)1Cwi/0 (conditional) |
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| B9d2/Tgfb1tm1Flv/Tgfb1tm2Flv Tnfrsf4tm2(cre)Nik/Tnfrsf4+ (conditional) |
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| Tgfb1tm1Doe/Tgfb1tm2.1Doe Tg(Lck-cre)548Jxm/? (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/14/2024 MGI 6.23 |
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